Inicetmay26/Neetpg26 on Instagram: "Late nyt part 2 Lets talk about GIST ke baare mein - Most GISTs have c-KIT (CD117) or PDGFRA mutation. # First-line drug 👉 Imatinib=DOCfor GIST But if: -Tumor becomes resistant to imatinib Or patient is intolerant ## Second-line drug👉Sunitinib=preferred drug for imatinib-resisGIST It inhibits: •c-KIT ,PDGFRVEGFR So it works even when imatinib fails."
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