A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes …

Jul 15, 2025 · Janus kinase (JAK) inhibitors are a group of medicines that help block immune system signals in the body that can lead to swelling (inflammation) and pain in conditions like …

Aug 23, 2025 · In this article, learn about the dosage, uses, and ongoing research underway for JAK inhibitors available in the United States, as well as common side effects, …

Jul 28, 2025 · The JAK-signal transducer and activator of transcription (STAT) pathway is central to immune dysregulation in many autoimmune diseases due to its role in transducing signals …

Feb 1, 2025 · Understanding the cell signaling pathway, and more specifically the JAK STAT pathway, is a breakthrough in the era of biotherapies. JAKi are increasingly designed to target …

Recently, Janus kinase inhibitors (JAKi) have been developed to block the effect of proinflammatory cytokines in IMIDs.

Aug 13, 2024 · Janus kinase (JAK) inhibitors are a group of medications with many uses. Rinvoq (upadacitinib), Xeljanz (tofacitinib), and Cibinqo (abrocitinib) are options for eczema and other …

Sep 9, 2024 · In this update, we discuss the background of JAK inhibitors, current approved indications and adverse effects, along with new developments in this field.

Janus kinase (JAK) inhibitors are a class of medications used to treat autoimmune and inflammatory conditions such as rheumatoid arthritis, psoriasis, and certain types of eczema. …

Some JAK inhibitors are used to treat cancer. They are a type of targeted therapy. Also called Janus kinase inhibitor.