Pancreatic cancer, also known as pancreatic ductal adenocarcinoma, is one of the most aggressive types of cancer. Despite ...
This study determined cryo-EM structures of midnolin-proteasome complexes, providing mechanistic insights to ...
Macrophages are highly plastic innate immune cells whose polarization and effector functions are tightly linked to their metabolic programs. Ubiquitination, the post-translational modification that ...
The Trump administration said the more complex test is the “first of many” changes to acquiring U.S. citizenship. By Jenny Gross The U.S. government will reinstate a harder citizenship test that ...
Damaged mitochondria release reactive oxygen species and pro-death factors which can lead to loss of cardiac myocytes. To protect against such damage, myocytes have developed several mechanisms of ...
Kymera Therapeutics has announced positive results in an early-stage Phase I trial for an investigational drug designed to treat millions of patients experiencing symptoms of chronic inflammation and ...
In the embryo, neurons must find and form connections with the appropriate synaptic partners as they wire circuits in the developing nervous system. To make these connections, axons must travel long ...
Cells, are you experiencing stress? Quick, SUMOylate your TDP-43 before it’s too late! Three independent papers appearing in rapid succession deliver the same message: Chain the small ubiquitin-like ...
Polycomb Repressive Complex 1 (PRC1) and Ubiquitin-Specific Protease 16 (USP16) have traditionally been recognized for their nuclear roles in chromatin regulation. However, our study reveals a ...
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