Increland has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an interleukin-1 receptor-associated kinase 4 (IRAK-4) ...

Powered by a 9.2 kWh battery, it features three driving modes and TVS SmartXonnect™ technology for real-time navigation and diagnostics. TVS launches e3-wheeler, priced at Rs 2.95 lakh.

If we had a penny for all the Halo E3 demos to be made publicly available, we’d have two pennies (Microsoft) Last November, Microsoft and 343 Industries (or Halo Studios as it’s now called ...

Importantly, AUCell analysis revealed that CHIP E3 ubiquitin ligase activity deficiency affected ubiquitin-mediated proteolysis, ultimately increasing the level of intracellular cAMP. The activation ...

Beyond Borders: Mobile Gaming Insights for Global Growth, a new interactive report by Moloco, reveals that mobile gaming app marketers tend to overfocus on large and well-established markets. By ...

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 ...

The authors demonstrate that nsp16 undergoes ubiquitination and subsequent degradation by the host E3 ubiquitin ligases UBR5 and MARCHF7 via the ubiquitin-proteasome system (UPS). Specifically, UBR5 ...

Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Institute of Developmental Biology and Regenerative Medicine, College of Chemistry and ...

The release also includes these new features: Connect to PostgreSQL: You can now let IAP Desktop connect to PostgreSQL and launch the psql command line client for you. A note to vim users: Because the ...

A lot of HP users are unable to print documents as the error code E3 pops up every time they try to do the same. In this article, we are going to see what you should ...