This study by Wu et al. provides valuable computational insights into PROTAC-related protein complexes, focusing on linker roles, protein-protein interaction stability, and lysine residue ...

that targets lysine-specific demethylase 1 (LSD1 or KDM1A), an enzyme crucial for cancer stem and progenitor cells, particularly in abnormal bone marrow cells. Bomedemstat is currently being ...

investigated the role of the E3 ubiquitin ligase ITCH in the life cycle of SARS ... ubiquitination of E and M impacts virus assembly and release. Identifying the specific lysine residues in M and E ...

It is “a good first step to start looking at the specific genes” that may affect speech and language development, said Liza Finestack at the US-based University of Minnesota, who was not ...

NOVA1 may be a bona fide human 'language gene,' though certainly it's only one of many human-specific genetic changes." Robert B. Darnell, head of the Laboratory of Molecular Neuro-Oncology ...

Acetylation is a PTM where an acetyl group (COCH3) is added to a protein, typically at lysine residues, altering its function ... Strategies aimed at targeting specific PTMs could not only enhance the ...