The Scientist4mon
DNA Polymerase Works in Short Bursts Rather than One Long Stretch
Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...
Nature4y
DNA Transcription
Transcription of eukaryotic genes by polymerases I and III is initiated in a ... Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding ...
Scientists Capture First-Ever Images of Cancer’s Covert DNA Repair Strategy
A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...
Nature2y
RNA Transcription by RNA Polymerase: Prokaryotes vs Eukaryotes
Specifically, in eukaryotes, transcription is achieved by three different types of RNA polymerase (RNA pol I-III). These polymerases ... RNA pol II can bind to a DNA sequence within the promoter ...
The Scientist4mon
A Novel Polymerase Reduces Stutter in Forensic DNA Analysis
Forensic DNA profiling uses polymerase chain reaction (PCR) to amplify short tandem repeats (STRs), which are highly variable DNA regions, typically with four repeating bases. This variability helps ...
eLife10d
Transcription: The plusses and minuses of DNA torsion
A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.