Metzger MB, Pruneda JN, Klevit RE, Weissman AM (2013) RING‐type E3 ligases: master manipulators of E2 ubiquitin‐conjugating enzymes and ubiquitination. Biochim Biophys Acta pii:S0167‐4889(13)00216‐4.

The human genome encodes hundreds of E3 ubiquitin ligases, which are classified into 3 main classes based on structural similarities: the RING-finger proteins (the most abundant class of E3 enzymes), ...

In yeast, the E3 ubiquitin ligases HRD1 and DOA10 make use of an ER-resident HSP70-binding protein 3 (BiP3) to survey client ERAD substrates other than HMGR (Ruggiano et al., 2014). The DOA10 complex ...