E3 ubiquitin-protein ligase CBL-B promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in ...

Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic reticulum ‐associated degradation. In mammals, Synoviolin plays crucial roles in various physiological and ...

Apple E3 ligase MdPUB23 mediates ubiquitin-dependent degradation of MdABI5 to delay ABA-triggered leaf senescence. Article Publication Date. 30-Jan-2024. COI Statement.

In this webinar, brought to you by Bio-Techne, Jennifer Johnston will discuss how her research of ubiquitin-proteasome system elements, including Parkin E3 ligase, is used to diagnose and treat ...

In addition to the observed DDB1-COP1/SPA protein-protein interactions, genetic evidence also strongly supports that COP1/SPA acts as part of a CUL4-based E3 ubiquitin ligase. Viable, hypomorphic cul4 ...

Plants have an internal time keeper known as the circadian clock that operates in 24-hour cycles to coordinate the plants behaviors with the environment. The clock is made of many different proteins ...

Proteomic, biochemical and cell-based analyses of the heterodecameric core GID/CTLH E3 ligase complex reveal its molecular architecture, activity determinants, and function in targeting the tumor ...

Keywords: abiotic stress, AtSIZ1, COP1, E3 ubiquitin ligase, E3 SUMO ligase, post-translational modification, SUMO, SUMO conjugate. Citation: Kim JY, Jang I-C and Seo HS (2016) COP1 Controls Abiotic ...

Role of Ubiquitin Ligases and the Proteasome in Oncogenesis: Novel Targets for Anticancer Therapies. JCO 31 , 1231-1238 (2013). DOI: 10.1200/JCO.2012.44.0958 ...