The San Francisco 49ers quarterback and his wife are enjoying the offseason in a rare glimpse of them together.

It looked in the middle of the season like the San Francisco 49ers and Arizona Cardinals may be playing for the NFC West crown in Week 18. The opposite turned out to be true.

The Arizona Cardinals concluded their NFL regular season schedule with a decisive 47-24 victory over the San Francisco 49ers Sunday at State Farm Stadium.

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

The Cardinals are 1-5 since the bye week but have a chance to finish strong against the 49ers on Sunday afternoon in Glendale.

The 49ers season ends with a 47-24 defeat that showcases all the reasons they lost 11 games. A gassed defensive line gives up 21 points in the 4th quarter. The quarterback turns the ball over ...

The San Francisco 49ers’ current window might have closed, but if the ongoing NFL playoffs tell them anything, it’s that another window could open soon.

Kyler Murray tied a career high with four touchdown passes and did not throw an interception Sunday to lead the Arizona Cardinals to a 47-24 victory and season sweep of the San Francisco 49ers at ...

The San Francisco 49ers will face the Arizona Cardinals in week 18 of the NFL season at State Farm Stadium on Sunday, January 5th. WATCH: 49ers vs Cardinals Live | Stream free on Fubo The 49ers did ...

SANTA CLARA — The 49ers will be without some key players when they visit the Arizona Cardinals Sunday to close out the regular season. Which sounds about right for a 6-10 team that has 15 ...

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?

Brock Purdy and the San Francisco 49ers’ brass have a similar mindset regarding one of the biggest offseason questions around the organization.