The NEURL E3 ubiquitin ligases selectively activate the Notch ligands DLL1 and JAG1, but not DLL4 and JAG2. This differential ...

This study determined cryo-EM structures of midnolin-proteasome complexes, providing mechanistic insights to ...

A new study has identified TRIM56, an E3 ubiquitin ligase, as a key activator of the proto-oncogene Src in hepatocellular carcinoma.

The winners of the prestigious in-cosmetics Asia 2025 Awards have just been revealed, celebrating the most innovative cosmetic ingredients launched within the last eight months.A record-breaking 120 ...

Pancreatic cancer, also known as pancreatic ductal adenocarcinoma, is one of the most aggressive types of cancer. Despite ...

The study reveals a new regulatory mechanism controlling the biosynthesis of tanshinones and phenolic acids in Salvia ...

Research in the field of ubiquitination has unveiled it as a fundamental post-translational modification mechanism that meticulously directs protein fate ...

Researchers showed that large motor neurons face high metabolic stress, making them more prone to degeneration. Reducing this ...

Fertility: Research suggests p53 may play a role in female fertility and reproductive health. Therefore, p53 is a crucial ...