TRIF also promotes the TRAF3-dependent activation of the ... Therefore, the detailed mechanisms of how these polyubiquitin chains activate the kinase complex during TLR signaling pathway activation ...

The research could ultimately lead to targeted treatments for alcohol-related sleep loss, helping people recover from alcohol ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

Proper functioning of the JAK2-STAT5 signaling pathway relies on crosstalk with other signaling pathways (synergistically or antagonistically), which leads to normal biological performance. This ...

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, ...

Types of cell signalling pathways include checkpoint signalling, lipid signalling, growth signalling, nutrient signalling, insulin signalling, stress signalling, morphogen signalling, Hippo ...

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Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...