Vitamin E succinate has been found to inhibit tumor growth and enhance the effectiveness of immunotherapy by targeting ...

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing ...

Multiple myeloma (MM) is a hematologic malignancy of bone ... CRL4 (Cullin-RING ubiquitin ligase) is an E3 ubiquitin ligase, composed of three subunits DDB1, cullin 4 (CUL4), and regulator of cullins ...

Multiple layers of regulation modulate the ... USP44 deubiquitylates CDC20, a co-activator of the E3 ubiquitin ligase anaphase promoting complex or cyclosome (APC/C) that promotes the degradation ...

These small drug compounds destabilise proteins by bringing them into proximity with enzymes called E3 ubiquitin ligases that cause ... in blood cancers like multiple myeloma.

Poxviruses have evolved a variety of innate immunity evasion mechanisms, some of which involve poxvirus-encoded E3 ubiquitin ligases and adaptor proteins. Based on their functional domains and ...

Powered by a 9.2 kWh battery, it features three driving modes and TVS SmartXonnect™ technology for real-time navigation and diagnostics. TVS launches e3-wheeler, priced at Rs 2.95 lakh.