Shenzhen Zhongge Biotechnology Co. Ltd. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an interleukin-1 ...
Katalytic Therapeutics Inc. has divulged proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to a phosphodiesterase PDE4-targeting ...
TRIMTECH Therapeutics’s incredible $31million seed funding haul will be deployed to develop treatments for severe ...
AZoLifeSciences on MSN6d
Investigating Ubiquitination's Role in Cancer Stem Cell RegulationThis review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), ...
After the presentations at the 2025 #21ToWatch ceremony at Botanic House there was a chance to meet the winners and - yes! - ...
and attachment to the substrate protein by ubiquitin ligases (E3s). Macrophages play a key role in atherosclerosis through lipid uptake and inflammation. Here, the authors show that RNF128 ...
This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...
This evening may see a few isolated showers, but tonight will then be dry with clear spells and a few patches of cloud. A few patches of mist and fog possible in spots too. Friday Tomorrow, cloud ...
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