Leveraging a novel protein tagging strategy offers new route to cancer treatment
In a pioneering collaboration with AbbVie, Northwestern researchers have discovered a new way to potentially treat cancer by ...
Medindia8h
Vitamin E Succinate Enhances Cancer Immunotherapy and Slows Tumor Growth
Vitamin E succinate has been found to inhibit tumor growth and enhance the effectiveness of immunotherapy by targeting ...
Vitamin E succinate shown to control tumor growth and enhance immunotherapy effects
High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
News Medical on MSN1d
Study identifies vitamin E succinate as key to tumor growth control
High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
technologynetworks1d
Vitamin E Succinate Helps Control Tumor Growth and Enhance Immunotherapy
Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing ...
Medindia18h
MYCN and MDM2: A Transformative Strategy in Cancer Therapy
Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.
C&EN5d
3,3′-Diindolylmethane (DIM): A Molecular Scaffold for Inhibition of WWP1 and WWP2, Members of the NEDD4 Family HECT E3 Ligases
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom ...
The EMBO Journal4d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Nature1d
Target identification articles from across Nature Portfolio
Target identification is the process of identifying the direct molecular target – for example protein or nucleic acid – of a small molecule. In clinical pharmacology, target identification is ...
Nature2d
Cellular neuroscience articles from across Nature Portfolio
Caspases are known to mediate neuronal apoptosis during brain development. Here authors demonstrate a role for nonapoptotic caspase-3 activation in neurons with elevated activity, in the promotion ...