Lac directly binds the E3 ligase STUB1, leading to increased polyubiquitination and proteasomal degradation of RUNX1. Lac inhibits Tregs activity and promotes antitumor immunity in a mouse primary ...

E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Technology developed in symbiosis with the natural world to meet the challenges of our time and create a more sustainable future E3 – Balanced Solutions for a Better World As a university we have a ...

Office 365 E5 is a cloud-based suite of Microsoft 365 productivity apps combined with advanced voice, analytics, security, and compliance services. Install Microsoft 365 on up to five PCs or Macs, ...