Comparative genomic hybridization (CHG) provides the densest coverage of probes for CNV detection, but the traditional technique using bacterial artificial chromosome arrays is time consuming and not ...

Here, we discuss the state of the art of array comparative genomic hybridization and its applications in cancer, emphasizing general concepts rather than specific results.

Array-based comparative genomic hybridization is able to unveil previously undetectable nuances.

Moreover, when CNVs are suspected, custom array CGH can detect the exact range of CNVs. These genetic analysis tools have enabled us to diagnose almost all inherited kidney diseases. In this lecture, ...

Roche NimbleGen CGH arrays offer expanded probe coverage in these regions. Using this technique, the authors of a recently published paper identified a recurrent reciprocal genomic rearrangement of ...

In clinical diagnostics, both array comparative genomic hybridization (array CGH) and single nucleotide polymorphism (SNP) genotyping have proven to be powerful genomic technologies utilized for ...

Principals of Array CGH & SNP Arrays Array CGH uses competitive hybridization of fragmented tumor DNA and control DNA labeled with different fluorophores to a microarray platform to detect CNAs.

Microarray based comparative genomic hybridisation (array CGH) is a new technology with uses developing in various diagnostic areas within the NHS. One important context is the investigation of ...

They recommended that advanced genomic technologies, such as array CGH, be broadly deployed by cell culture banks to ensure consistency of the cells they provide to the research community.

Scientists using an Agilent custom-designed comparative genomic hybridization array have sequenced the entire gene map of a Korean male.

DNA was analyzed by CGH array, and gliomas were genetically classified according to the following criteria, as previously described 3: group A corresponded to 1p19q codeleted tumors; group B ...

Detection of CNAs in AML As with MDS, early studies in AML with array CGH and SNP array showed the feasibility of interrogating AML genomes with array platforms and demonstrated their utility in ...