The San Francisco 49ers fell to the Los Angeles Rams, and while the defense should get most of the blame, George Kittle put ...

The San Francisco 49ers may get their top wide receiver back for a Week 11 showdown with the Arizona Cardinals.

What's the Arizona Cardinals vs Seattle Seahawks score? Follow our live score updates for latest news, highlights, analysis ...

Head coach Kyle Shanahan on Monday confirmed the club had a tryout with free agent cornerback Asante Samuel Jr., the son of four-time Pro Bowler and First-Team All-Pro CB Asante Samuel.

Sunday was largely unkind to San Francisco. But, the 49ers had several standout performers in its loss versus the Los Angeles Rams.

San Francisco 49ers starting quarterback Brock Purdy won't be active again Sunday vs. the Los Angeles Rams according to a ...

The Detroit Lions beat the Washington Commanders 44-22 on Sunday, Nov. 9, in Week 10 of the NFL season. Here are the ...

The San Francisco 49ers entered their second matchup against the Los Angeles Rams as underdogs and lost. Here were the worst ...

San Francisco 49ers head coach Kyle Shanahan doesn't have a return date for Brock Purdy, but he gave insight on what the team needs to see from him.

How close was Brock Purdy to playing vs. the Rams? Kyle Shanahan updated his injury status after the 49ers fell against LA.

The San Francisco 49ers have already lost Fred Warner for the year, and now they may have to play without his replacement.

Dan Campbell told Fox at halftime "we wanted to mix things up" on offense. He said he was calling plays in Detroit Lions game ...