3 Working Group ‘Deep Brain Stimulation in Psychiatry: Guidance for Responsible Research and Application’. This Working Group is organised by the Europäische ...

4 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden Background Alzheimer's disease (AD) ...

The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour. Apathy occurs ...

3 UK Dementia Research Institute at Edinburgh, The University of Edinburgh, Edinburgh, UK 4 The Usher Institute, The University of Edinburgh, Edinburgh, UK Background Inflammatory responses to ...

Correspondence to: Dr E H Reynolds, Institute of Epileptology, Weston Education Centre, King's College Denmark Hill Campus, Cutcombe Road, London SE5 9PJ, UK During three decades of neurological ...

Background Deep brain stimulation (DBS) of the globus pallidus interna (GPi) is a highly efficacious treatment for cervical dystonia, but its mechanism of action is not fully understood. Here, we ...

OBJECTIVES Increased resistance to stretch of muscles after stroke may be the result of centrally mediated neural factors such as spasticity or local, peripheral factors such as muscle contracture or ...

Dr JL Iddon, Department of Academic Neurosurgery, Box 167, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 5RG, UK email jo.iddon{at}cenes.co.uk OBJECTIVES Eleven patients ...

1 Rush Institute for Healthy Aging, Centers for Disease Control and Prevention, Atlanta, GA, USA 2 Department of Internal Medicine, Centers for Disease Control and Prevention, Atlanta, GA, USA 3 ...

Background Total bilirubin (TBIL) has antioxidant and anti-inflammatory properties. This study aimed to determine whether elevated TBIL could modify the association between diabetes and stroke. Method ...

Background Biological ageing is one of the principal risk factors for neurodegenerative diseases. It is becoming increasingly clear that acceleration of DNA methylation age, as measured by the ...

Objective To test the hypothesis that imaging signs of ‘brain frailty’ and acute ischaemia predict clinical outcomes and symptomatic intracranial haemorrhage (sICH) after thrombolysis for acute ...