ATLANTA -- A novel antisense mRNA drug slashed triglycerides in higher risk or moderate hypertriglyceridemia patients and in those with extremely elevated levels from familial chylomicronemia syndrome ...
In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary ...
Hypertriglyceridemia, or high levels of lipids (fats) in the blood, increases the risk of heart attack, stroke and acute pancreatitis. Currently available medications, including statins, ezetimibe, ...
A drug that specifically targets liver LXR Now, scientists led by Johan Auwerx at EPFL and Mani Subramanian at OrsoBio have addressed this problem with an orally administered compound that can repress ...
Patients with the genetic recessive disorder persistent chylomicronemia who received the investigational drug plozasiran had significantly lower triglyceride levels and a reduced risk of acute ...
Jonathan Wosen is STAT’s West Coast biotech & life sciences reporter. You can reach Jonathan on Signal at jwosen.27. Ionis Pharmaceuticals reported on Tuesday that a drug approved for a rare disease ...
Researchers from Mass General Brigham have found that olezarsen-a drug designed to lower triglyceride levels-can also decrease the risk of acute pancreatitis, a potential complication in patients with ...
Despite experiencing significant reductions in triglycerides, patients with triglycerides over 150 mg/dL and a high risk of atherosclerosis did not experience any significant change in the amount of ...
Discussions about heart health often center around blood pressure and cholesterol, with factors like poor sleep, smoking, family history of heart disease, and chronic stress thrown in. However, ...
Experts have found a new type of cholesterol. And it could be the most dangerous ...
In a small, short-term, Phase 2 clinical trial in adults, a first-of-its-kind medication reduced triglyceride levels in most patients by more than 60%. Called DR10624, the medication activates three ...