Shortly after this Review was completed, we were saddened to learn that Dr Tao-shih Hsieh, of Duke University, Durham, North Carolina, USA, and Academia Sinica, Taipei, passed away. Hsieh was a true ...
This review examines the cellular functions of the DNA topoisomerases from a mechanistic point of view. The following points are summarized. Classification of DNA topoisomerases into four subfamilies ...
Cambridge, MA, November 15, 2012 – A group of researchers at the University of California, Berkeley have for the first time described the structure of the active site core of topoisomerase II alpha, ...
This is a preview. Log in through your library . Abstract Topoisomerases type I and type II are enzymes that unwind and wind DNA, in order to control the synthesis of proteins. Therefore, targeting ...
The Plant Cell is in its 19th year of publication. Within three years of its initial publication, it ranked first in impact among primary research journals in the plant sciences, a standard of ...
The current pandemic of COVID-19 has taken 1.5 million lives and counting while causing many more people to fall ill. Many studies have shown that adverse outcomes are related to excessive levels of ...
Identifying the primary site using gene expression profiling in patients with carcinoma of an unknown primary (CUP): a feasibility study from the GEFCAPI ...
Primary Analysis of EPIK-O/ENGOT-ov61: Alpelisib Plus Olaparib Versus Chemotherapy in Platinum-Resistant or Platinum-Refractory High-Grade Serous Ovarian Cancer Without BRCA Mutation Heavily ...
Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are ...
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