Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.

Researchers from The University of Osaka found that the zinc finger proteins RLF and ZFP292 play redundant roles in ...

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation.

Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.

“Our findings show that intestinal stem cells are not only responsible for tissue regeneration, but also the early defense ...