Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

When a gene is active, there is cellular machinery that transcribes the sequence of that gene from DNA into messenger RNA. This is a fundamental cellular process that is essential to the proper ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have made a new discovery about how human cells make RNA, a molecule that functions as a set of blueprints that tell cells how to ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems. Fungal ...

A research team from The Hong Kong University of Science and Technology (HKUST) has made an advance in understanding the molecular machinery of RNA silencing. The team uncovered how the human enzyme ...

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...