Then an enzyme called poly-A polymerase adds a chain of adenine nucleotides to the RNA. This process, called polyadenylation, adds a poly-A tail that is between 100 and 250 residues long.

RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription. As complex molecule composed of protein subunits, RNA ...

The RNA polymerase has two regions in which the lysine residues are arranged in a line. They found that these lysine residues correspond to two of the three paths.

SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces double ...

Intrinsic cleavage of RNA polymerase II adopts a nucleobase-independent mechanism assisted by transcript phosphate. Nature Catalysis, 2019; 2 (3): 228 DOI: 10.1038/s41929-019-0227-5; ...

In the latest shake-up for scientific dogma, research has demonstrated that eukaryotic cells can convert RNA sequences back into DNA, through a misunderstood, ‘error-prone’ polymerase. Historically, ...

Functional RNA Studies Are a Useful Tool in Variant Classification but Must Be Used With Caution: A Case Study of One BRCA2 Variant. ... Poly (ADP-Ribose) Polymerase Inhibitor Activity in Prostate ...

The RNA-dependent RNA polymerase of the novel coronavirus is a complex that includes the small proteins nsp7 and nsp8. Researchers studying SARS-CoV-2, the novel coronavirus that causes ...

A Synthetic Lethal Therapeutic Approach: Poly(ADP) Ribose Polymerase Inhibitors for the Treatment of Cancers Deficient in DNA Double-Strand Break Repair. JCO 26 , 3785-3790 (2008). DOI: ...