Trial results show setrusumab reduces the incidence of fracture and increases bone density and formation. The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to ...

Please provide your email address to receive an email when new articles are posted on . The classification system associated with prenatally diagnosed osteogenesis imperfecta may be outdated. Modern ...

Setrusumab did not meet primary fracture endpoints in the ORBIT and COSMIC trials but significantly improved bone mineral density in patients with osteogenesis imperfecta. Topline data were announced ...

Add Yahoo as a preferred source to see more of our stories on Google. Maybe you heard about it after watching the Samuel L. Jackson movie "Unbreakable." Or maybe after binging Season 11 of "Grey's ...

A new paradigm has emerged for osteogenesis imperfecta as a collagen-related disorder. The more prevalent autosomal dominant forms of osteogenesis imperfecta are caused by primary defects in type I ...

Skeletal deformity and bone fragility are the hallmarks of the brittle bone dysplasia osteogenesis imperfecta. The diagnosis of osteogenesis imperfecta usually depends on family history and clinical ...

Parents, have you ever heard of osteogenesis imperfecta? This is a disease that often attacks bones. This disorder can attack children from birth. Osteogenesis imperfecta also has many types with ...

A new study led by Baylor College of Medicine identifies an underlying mechanism of pathogenesis for osteogenesis imperfecta (OI) in human bone. The report, published in the Journal of Clinical ...

Osteogenesis imperfecta is a heritable disorder that causes bone fragility. Mutations in type I collagen result in autosomal dominant osteogenesis imperfecta, whereas mutations in either of two ...

Classic osteogenesis imperfecta, an autosomal dominant disorder associated with osteoporosis and bone fragility, is caused by mutations in the genes for type I collagen. A recessive form of the ...

Melanie Watson Bernhardt, best known for her role in Diff’rent Strokes, died on Friday. She was 57. According to her brother, the actress, who played the character of Kathy Gordon on the hit 80s ...

Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare genetic disease affecting the connective tissue and bones. In this disease, bones become extremely fragile and break or ...