Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...

Insulin resistance arises when insulin-sensitive tissues—principally adipose, skeletal muscle and liver—fail to respond appropriately to insulin’s signals to promote glucose uptake and to suppress ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

A newly discovered mechanism that leads to liver dysfunction may be a key factor in type 2 diabetes and other metabolic disorders in individuals with obesity, according to a new study led by Harvard T ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Today millions of diabetic patients across the world do not have access to insulin. Why and how can governments reverse this phenomenon?

Hidden chemical compounds found in everyday plastics could biochemically alter metabolic pathways to trigger insulin ...

Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include stimulation ...

A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...