The methylenetetrahydrofolic acid reductase (MTHFR) C677T polymorphism causes an amino-acid change from alanine to valine and results in the enzyme becoming thermolabile and half decreased activity.

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. The C677T in the gene that encodes MTHFR decreases the activity of ...

Background: The enzyme MTHFR catalyses the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, which serves as a methyl donor in the reaction converting homocysteine ...

Plasma B-group vitamins and age may affect the carotid intima-media thickness (IMT) in subjects with different 677TT genotype of the methylenetetrahydrofolate reductase (MTHFR) gene. Healthy subjects ...

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo genetic ...

Depression. Autism. Breast cancer. Alcoholism. Type 1 diabetes. Heart disease. What do these supposedly have in common? Many alternative health websites like to talk about a supposed link between ...

Did you know that a significant percentage of the U.S. population has one of the less-efficient variants of the MTHFR gene? TikTokers love to say this, and it’s true. They’ll also claim that if you ...

Shared tens of thousands of times on Facebook, posts claim that three conditions found in infants – stork bites, sugar bugs, and sacral dimples – indicate a mutation in the MTHFR gene. The posts also ...

MTHFR is the acronym for a gene (methylenetetrahydrofolate reductase) that produces an essential enzyme. The acronym for the enzyme is also MTHFR. It’s worth knowing about this gene because it plays a ...

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to health issues, such as ...