Trulance (plecanatide) and Linzess (linaclotide) are brand-name prescription medications. They’re approved by the Food and Drug Administration (FDA) to treat certain types of constipation. Trulance ...

Trulance and Linzess are prescription medications for adults that treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). They have similar safety and ...

Linzess may interact with anticholinergic drugs, such as oxybutynin (Ditropan XL), and antidiarrheal drugs, such as loperamide (Imodium). Taking these drugs with Linzess can make Linzess less ...

Linzess (linaclotide) is a brand-name oral capsule that’s prescribed for certain digestive system issues, including some types of constipation. As with other drugs, Linzess can cause side effects, ...