The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

When most people think about insulin resistance, sugar is usually the first thing that comes to mind. And while excessive ...

Dr. Kaitlyn R. Shank (Medicine): A 46-year-old woman was admitted to this hospital because of hyperglycemia that was refractory to insulin therapy. Five years before the current presentation, the ...

In nerve cells, the hormone regulates whether mitochondria are shut down or kept running. The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One ...

Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to advance his research on viral insulins into the understanding ...

Explore Tesamorelin, a synthetic GHRH analog shaping research on growth hormone regulation, lipid metabolism, IGF-1 signaling ...

Striking the right balance: in nerve cells, the hormone insulin and the protein PINK1 control whether cellular power plants are kept running or whether they are shut down. The hormone insulin controls ...