Single-cell RNA sequencing (scRNA-seq) is an important technology that reveals gene expression differences between different cell types. Yet scRNA-seq data can be challenging to analyze and interpret.
Assays to measure homologous recombination deficiency (HRD) in ovarian cancer vary widely, underscoring the need for standardization, since inconsistent assay results can influence treatment decisions ...
Scientists uncover the ovarian cancer cause behind drug resistance and immune therapy failure - here's what the latest 2026 ...
High-grade serous ovarian cancer (HGSOC) often originates in the fallopian tube fimbriae, not the ovarian surface epithelium. Opportunistic salpingectomy is recommended during benign gynecologic ...
Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that ...
Research led by Memorial Sloan Kettering Cancer Center (MSK) is shedding new light on how ovarian cancer evolves—insights that could help researchers develop more effective treatment strategies. While ...
Ovarian carcinomas have the highest mortality rate among gynecological cancers, and high-grade serous ovarian carcinoma (HGSOC) accounts for 70–80% of ovarian cancer deaths during several decades [1].
Tissue Proteomics and Custom-Made Transcriptomics Analysis Tool Revel PPP1R12B, FBLN5, CRIP2, and POSTN as Potential Prognostic Biomarkers in Prostate Cancer High grade serous ovarian cancer (“HGSOC”) ...
The study provides proof of principle for a novel approach to early detection of ovarian cancer based on an assessment of genomic instability patterns in DNA from Papanicolaou (Pap) smears. Findings ...
High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it ...
Treatment of high-grade serous ovarian cancer (HGSOC) remains challenging. Although HGSOC can potentially be responsive to immunotherapy owing to endogenous immunity at the molecular or T cell level, ...