Patients with solid tumors, such as breast and gastrointestinal cancers, who also have clonal hematopoiesis of indeterminate potential could have a significantly higher risk for cardiovascular disease ...

Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors The article by Boettcher et al entitled “Clonal ...

Prognostic Value of Neurotrophic Tyrosine Receptor Kinase Gene Fusions in Solid Tumors for Overall Survival: A Systematic Review and Meta-Analysis Recent larger-scale studies of patients with cancer ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...

The decrease in the incidence of cardiovascular disease and the improved prognosis in persons with a diagnosis of cardiovascular disease are due, in part, to the development of new treatments based on ...

Researchers from the University of Toronto (Canada) have presented a new high-resolution gene expression atlas that shows the normal differentiation process of hematopoietic cells at the American ...

Hematopoiesis, the biological process of blood cell formation, has long attracted the attention of mathematicians and biomedical researchers alike. Recent work in this arena has increasingly focused ...

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal ...

Hematopoiesis is the process of blood cell renewal in the body and occurs throughout adulthood. Growth factors enable the tight regulation of hematopoiesis, enabling new blood cells to differentiate, ...