Helicases are enzymes that unwind DNA and RNA. They’re central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs. Now, new ...

In a new paper published in the April 30 issue of the journal Science, a group of researchers from the Case Western Reserve University School of Medicine provide fundamental new insight into the ...

Scientists have solved the structure of the Zika virus helicase, which is a key target for antiviral development. A team led by researchers from Tianjin University (P.R. China) has solved the ...

RNA helicases are a group of enzymes that bind to and alter RNA in an ATP-dependent way. They play significant roles in RNA metabolism, gene expression regulation, and innate immunity. Different RNA ...

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections - and, alas, extraordinarily difficult to target with drugs. Now, new ...

CHAMPAIGN, Ill. – Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme.

Mutated Hrq1 and Pif1 helicase enzymes shown to work together to disrupt telomere maintenance and regulation of cell division. All strands of DNA have a non-coding region at the end of the strand ...

A DNA sequence that acts as a throttle to control the rate at which an enzyme moves along the DNA has been observed by researchers at UC Davis. By controlling the activity of the RecBCD helicase ...

Caenorhabditis elegans, the roundworm in question, may not look much like humans since they measure just one millimeter in length, but a number of their biological processes are similar to ours. In ...

Using some extraordinary camera tricks, scientists at the University of California at Davis have produced Lilliputian action shots of molecular "motors" unwinding strands of DNA. Close to four years ...