Bacterial superantigens (bSAgs) bind as folded proteins to both major histocompatibility complex (MHC) class II molecules on the surfaces of antigen–presenting cells and T cell receptor Vβ domains on ...
Patients in UKALL XI were simultaneously recruited by the UK Childhood Cancer Study, 20 an independent case–control epidemiological study designed to assess the impact of environmental carcinogen ...
HLA-Arena can be integrated in computational pipelines to support basic cancer research or to help inform physicians in preclinical settings. It can be used to perform structure-based selection of ...
LTX-315, an oncolytic peptide, to convert immunogenically ‘cold' tumors to ‘hot' in patients with advanced or metastatic tumours: Results from an ongoing phase I study. This is an ASCO Meeting ...
One third of organ transplants are lost to transplant rejection. Although acute transplant rejection responds relatively well to steroids, chronic rejection (which is mainly mediated by antibodies) ...
To the Editor: Loupy et al. (Sept. 26 issue) 1 present data showing that the C1q-binding assay is more sensitive than the standard complement-dependent microlymphocytotoxicity (CDL) assay for ...
HLA (Human Leukocyte Antigen) typing is important in organ transplantation protocols, as they determine the likelihood of rejection. The HLA system is little understood, however. In simple terms, the ...