Overexpression of focal adhesion kinase (FAK) is linked to worse prognosis and greater risk of metastasis in colorectal, cervical, breast and skin cancers. Despite its attractiveness as a therapeutic ...
Graphical illustration depicting the multifaceted role of FAK in cancer. FAK is activated by integrins, RTKs, and GPCRs, driving downstream oncogenic processes including proliferation, EMT/invasion, ...
Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial Eligible patients whose tumors ...
Comprehensive germline and somatic DDR genomic profiles of Chinese patients with multiple primary lung cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does ...
“Cell migration is required and essential for metazoan development, tissue regeneration and repair, as well as in immune surveillance. Many diseases such as cancer, fibrosis, and inherited ...
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