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These 3D model brains with cells from several people are first of their kind Chimeric brain ‘organoids’ promise to help reveal individual variation in brain development and in drug responses.
Miniature models of the brain have revealed a "previously unappreciated" role of microglia, a type of cell found within the organ. The finding could help unpack how disorders such as autism arise.
Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological conditions, ...
Engineered 3D skin model successfully simulates early wound healing, offering insights into inflammatory responses and potential therapeutic applications.