In 2020, Jennifer Doudna won the Nobel Prize in chemistry for her work on the CRISPR-Cas9 gene-editing technology that allows ...

Potent drugs like chemotherapy can be life-saving, but often with life-threatening side effects. Notably, they can be ...

Researchers in Leiden have, for the first time, observed how a specialized enzyme helps bacteria stay alive when oxygen ...

Computer algorithms have designed highly efficient synthetic enzymes from scratch, with minimal need for tedious hands-on experiments to perfect them. The resulting enzymes catalyse a chemical ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to properly process cholesterol—something that breaks down during ...

Enzymes are proteins that guide (catalyze) very specific chemical reactions. They play indispensable roles in all life forms. Some enzymes carry out the day-to-day business of biology like digesting ...

Evolution is an extraordinary engine for enzymatic diversity, yet the chemistry it has explored remains a narrow slice of what DNA can encode. Deep generative models can design new proteins that bind ...

Researchers have discovered how acids on the surface of bacteria give these microscopic organisms their characteristic "rod" ...

Merck researchers developed a highly sustainable way to synthesize the macrocyclic peptide drug enlicitide, increasing ...

Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...