WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body. Published in Cell, the ...

Cell function is significantly influenced by a process called ubiquitination, in which molecules are selected for elimination ...

A team of researchers led by the Walter and Eliza Hall Institute of Medical Research has produced the first systematic catalog of human E3 ubiquitin ligases, the enzymes responsible for tagging ...

Their findings, published in a Cell Reports paper titled “Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation,” have implications for developing ...

Imagine trying to bake a cake without heat. You’ve got all the ingredients like flour, eggs and sugar, but nothing is happening. That’s what your body would be like without enzymes: potential but no ...

Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction required to make new ...

Scientists from The University of Manchester have uncovered a more efficient and sustainable way to make peptide-based medicines, showing promising effectiveness in combating cancers. Image Credit: ...

Researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells. The discovery could help to solve the mystery cause ...