In order for vertebrate embryos to develop their body axes, they require what is known as an embryonic signaling center. This group of cells provides the instructions that determine where up and down, ...

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children's in Los Angeles has identified a mechanism by which embryonic cells ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

In mammals, signalling between the placenta and the embryo is essential for successful development. Here, a quantitative, time-resolved model describes the coordinated formation of the mouse embryo ...

The discovery of a gene essential to early embryonic development sheds light on the preliminary stages of human placenta formation. A team led by scientists from the University of California San Diego ...

During embryo development, cells assess their position (positional information) by sensing different concentrations of a morphogen gradient; such gradients have been proposed to arise by diffusion ...

At the moment of fertilization, the genes in the fertilizing sperm and egg are switched off. For a new embryo to develop, they must be switched on—but how? The answer is unknown, which seems ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

Work by the team of Dr. Frédéric Charron recently published in The Journal of Neuroscience, identifies the fundamental role of a family of proteins, the β-arrestins, in the development of the nervous ...

Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized ...