Hamilton, ON - Canadian scientists studying the causes of atherosclerosis at the cellular level have shown that nitric oxide (NO) can be converted to peroxynitrite, an agent known to accelerate ...

The endoplasmic reticulum (ER) is central to protein synthesis, folding and modification, ensuring that the proteome of a cell remains functional and balanced. When the ER is overwhelmed by an ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

The bile acid and popular supplement, TUDCA, has the potential to reduce atherosclerosis — the buildup of fatty plaques in ...

As discussed above, there is considerable evidence from in vitro and in vivo studies that in a variety of tissues, hyperglycemia and possibly elevated FFA levels (both alone and in combination) result ...