Mechanistically, the E3 ligase BFAR suppressed cytokine-induced ... researchers found that targeting BFAR could not only revive the antitumor activity of aged CD8 + T cells, but also enhance ...
Covalent modification of the oncogene product Mdm2 by the ubiquitin-related protein SUMO1 protects it from ubiquitination and enhances its E3 ligase activity towards p53 in vitro. Disappearance of ...
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Understanding SARS-CoV-2's viral strategies for infectionis bound by SARS-CoV-2 ORF10 to increase its E3 ligase activity, leading to degradation of IFT46, a protein component of the intraflagellar transport (IFT) complex B. This results in dysfunctional ...
Analyst Gil Blum of Needham maintained a Buy rating on Nurix Therapeutics (NRIX – Research Report), reducing the price target to $28.00.Invest ...
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