The poster, titled Translational Insights from a First-in-Human Study of an Oral CBL-B Inhibitor in Advanced Solid Tumors, expands upon data presented at the recent European Society for Medical ...

The publication reports the highly selective, DCAF16 E3 enabled degradation of BRD9 in vivo using Amphista’s proprietary, next generation ...

The EXCALIBER-RRMM study evaluated the efficacy and safety of iberdomide, an investigational cereblon E3 ligase modulator, in combination with dexamethasone and daratumumab in adults with RRMM.

Recently, Prof. Si Longlong's team from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences constructed a library of live-attenuated influenza A vaccines that utilize ...

Nurix Therapeutics (NASDAQ: NRIX) underwent analysis by 13 analysts in the last quarter, revealing a spectrum of viewpoints ...

Thymus is the key organ for development and maturation of T lymphocytes. The dysfunction of thymus leads to decreased immunity or autoimmune diseases. T cells can be divided intoαβ T cells and γδ T ...

A new study has identified TRIM56, an E3 ubiquitin ligase, as a key activator of the proto-oncogene Src in hepatocellular carcinoma.

Traditional drug research has focused on creating inhibitors that occupy the active areas of disease-related proteins, preventing them from functioning properly. But this strategy leaves a ...

This is a preview. Log in through your library . Abstract Germline specification is the first step during sexual and apomictic plant reproduction, and takes place in the nucellus of the ovule, a ...

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced the publication of a ...