A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" ...

As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual ...

Dendritic cell sarcomas are rare neoplasms arising from antigen-presenting dendritic cells, most commonly the follicular subtype located within lymphoid germinal centres. They exhibit a broad ...

In the article that accompanies this editorial, van ‘t Land et al 24 report that additional pancreatic cancer adjuvant therapy with autologous, monocyte-derived dendritic cells (DCs) loaded with ...

Central epithelial nerve fiber density and related architectural metrics remain profoundly reduced up to two years post-LASIK, with parallel increases in mechanical (but not osmotic) sensory ...

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progr ...