As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading to symptoms of gut obstruction. There is currently no drug treatment ...

As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading to symptoms of gut obstruction. There is currently no drug treatment ...

LONDON: A new study has brought scientists closer to understanding why people with Crohn’s disease develop damaging scar tissue in their intestines, a complication that often leads to surgery.

UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s disease.

One barrier to progress in developing treatments for Crohn’s disease has been the lack of preclinical animal models that accurately replicate this complex autoimmune disorder. Another is the extreme ...