The complement system plays a crucial role in the innate defense against common pathogens. Activation of complement leads to robust and efficient proteolytic cascades, which terminate in ...

Although the complement system is primarily perceived as a host defence system, a more versatile, yet potentially more harmful side of this innate immune pathway as an inflammatory mediator also ...

After a slow start, the race is on to inhibit key proteins and pathways within the complement system -- a biological cascade that is central to the innate immune system and many different diseases ...

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye ...

Complement works with the immune system Proteins of the complement system react with each other to bind pathogens and trigger an inflammatory cascade response to fight infection.

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's ...

Researchers have identified a blood protein ‘signature’ in the complement system, part of the immune system, of patients with long COVID that may improve the diagnosis and lead to a treatment ...

An MUSC research team reports in Cells that the complement system, part of the body's natural immune defenses, is a key ...