In a recent Q&A, Matthew Lauber, a consulting scientist at Waters told us about the importance of accurately characterizing biotherapeutic proteins and discussed the most popular techniques.

As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods faster than ever before. Of all methods, charge variant analysis ...

Imaged isoelectric focusing (icIEF) has been established as the standard technique for profiling charge heterogeneity, which is a critical quality attribute (CQA) of biotherapeutics. The in-depth ...

Analyzing charge variants of biopharmaceuticals is a critical component of product development and quality control. Charge variants commonly occur as a result of both chemical and post-translational ...

Q: Why are glycans important? Answer: Many proteins undergo posttranslational modifications to incorporate oligosaccharides onto their surface. These carbohydrates known as glycans are attached ...