For the past 15 years or so, a class of drugs called immune checkpoint inhibitors have been used to treat melanoma – the most dangerous kind of skin cancer. For many patients, they produce remarkable ...

A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's ...

New research from the Francis Crick Institute and Adendra Therapeutics shows that immune cells can be redirected to recognise cancer by exploiting F‑actin, a structural protein exposed when tumour ...

When activated in ovarian cancer cells, the receptor for the body's primary stress hormone alters the tumor environment in ...

Investigators analyzed the immune-modulatory cancer vaccine IO102-IO103 plus pembrolizumab for PFS in patients with untreated advanced melanoma.

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the ...

Today, many people who receive cancer diagnoses have more treatment options than in the past. However, for some cancers, like pancreatic cancer, surgery and chemotherapy remain the only available ...