IMMUNOLOGIC abnormalities, including hypogammaglobulinemia, abnormalities of gamma 1 A globulin, poor homograft rejection and structural abnormalities of the thymus gland, have recently been reported ...

Affecting the nervous system, immune system and other body organs, ataxia telangiectasia is characterized with uncoordinated movements of the individual suffering from this disorder. The secondary ...

The modified amino acid levacetylleucine delivered clinically meaningful results in children and adults with the rare ...

Regulatory submissions planned in the US, Europe, and other jurisdictions for levacetylleucine in Ataxia-Telangiectasia, a neurodegenerative disease without any approved treatment and impacting ...

Monthly infusions of an investigational product that encapsulates dexamethasone sodium phosphate into autologous erythrocytes (EryDex) appeared safe but did not significantly improve neurological ...

Quince Therapeutics has disclosed outcomes from the Phase III ATTeST clinical trial of EryDex (dexamethasone sodium phosphate encapsulated in autologous erythrocytes) for treating ...

In the phase 3 NEAT trial, eDSP was well tolerated but did not significantly reduce neurological symptoms in patients with ataxia-telangiectasia. Topline data were announced from a phase 3 trial ...

An IgE deficiency was demonstrated in 11 of 16 patients with ataxia-telangiectasia. No relation to age or to the level of IgG, IgM or IgD was found. Nine out of 11 patients with IgE and IgA deficiency ...

Ataxia telangiectasia (AT) is a rare human disease characterized by extreme cellular sensitivity to radiation and a predisposition to cancer, with a hallmark of onset in early childhood. Several human ...

Should We Screen for Malignancies in People With ataxia telangiectasia? The following represents disclosure information provided by authors of this manuscript. All relationships are considered ...

Neurological deficits associated with liver disease may affect the peripheral nervous system and other systems in the body. This may increase a person’s risk of cancer, experience recurring infections ...