kidney A higher allopurinol dose provided a protective effect against incident renal failure in elderly patients, according to a study published in Annals of the Rheumatic Diseases. A higher ...

Opioid Use Linked to Low Testosterone In a Canadian study, more than half of older adults with CKD initiated allopurinol at a higher-than-recommended dose. Allopurinol doses exceeding 100 mg/d may ...

March 17, 2005 — High-dose allopurinol can prevent post–endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis, according to the results of a randomized study published in the March issue ...

There was an increase in all-cause mortality among dose escalators (hazard ratio, 1.08; 95% confidence interval, 1.01 to 1.17). Similar effect sizes were seen for incidence of cardiovascular-related ...

Please provide your email address to receive an email when new articles are posted on . Allopurinol dose escalation for patients with gout did not result in improved survival under the currently ...

In patients with gout, a novel prediction tool that relies on weight and creatinine clearance successfully identified the dose of allopurinol required to achieve a serum urate (SU) level < 6 mg/dL in ...

In a study of patients hospitalized with acute gout flares and who had prescriptions for allopurinol, those who had their allopurinol dosages decreased had a higher rate of gout flares within 3 months ...

Please provide your email address to receive an email when new articles are posted on . “There are no clear data to suggest that allopurinol is detrimental to renal function in patients with gout,” ...

Allopurinol is currently used as urate-lowering therapy in patients with gout. Findings suggesting that allopurinol-related toxicity is associated with impaired renal function have led to the ...

A study of over 100,000 gout patients has found that urate-lowering drugs, particularly allopurinol, are linked to a significant reduction in the risk of heart attack and stroke when taken at the ...

The effects of allopurinol treatment on mortality among patients with gout remain uncertain, with a new meta-analysis finding conflicting results. In a systematic review of the literature that ...

Allopurinol inhibits the generation of oxygen-derived free radicals and it has been postulated that this xanthine oxidase inhibitor might prevent post-endoscopic retrograde cholangiopancreatography ...