The matchups for the third annual ACC/SEC Challenge were announced Wednesday, highlighted on the men's side by Duke hosting reigning national champions Florida and multiple potential top-10 matchups on the women's side.

ACC/SEC Challenge was an unmitigated disaster for the ACC, which limped to a 2-14 mark in the second year of the challenge. It portended the doom that was to come for the ACC, which had just one of its four teams survive the first round of the NCAA Tournament.

The Florida Gators will face Duke in a marquee 2025 ACC/SEC Challenge game, setting up a high-profile nonconference matchup. Here's what to know.