The San Francisco 49ers quarterback and his wife are enjoying the offseason in a rare glimpse of them together.

SANTA CLARA — The 49ers will be without some key players when they visit the Arizona Cardinals Sunday to close out the regular season. Which sounds about right for a 6-10 team that has 15 players on ...

The Arizona Cardinals concluded their NFL regular season schedule with a decisive 47-24 victory over the San Francisco 49ers Sunday at State Farm Stadium.

It looked in the middle of the season like the San Francisco 49ers and Arizona Cardinals may be playing for the NFC West crown in Week 18. The opposite turned out to be true.

The 49ers season ends with a 47-24 defeat that showcases all the reasons they lost 11 games. A gassed defensive line gives up 21 points in the 4th quarter. The quarterback turns the ball over ...

Arizona adds to more of the misery to ensure the 49ers finish last in the division. Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose. While we do ...

The Cardinals are 1-5 since the bye week but have a chance to finish strong against the 49ers on Sunday afternoon in Glendale.

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

The San Francisco 49ers’ current window might have closed, but if the ongoing NFL playoffs tell them anything, it’s that another window could open soon.

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, streaming Sunday.

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?

Brock Purdy and the San Francisco 49ers’ brass have a similar mindset regarding one of the biggest offseason questions around the organization.